
Thesis topic:
Application of on-line biosensors in monitoring of drinking water quality
Motivation
Solution
The solution is the development and application of ultrasensitive electrochemical biosensors, where the basis is made from boron-doped nanocrystalline diamond layer ("BDNCD"), which is immobilized by sensors biomolecules such as antibodies, proteins, carbohydrates, or DNA oligonucleotides. These biomolecules are able to interact with bacterial cell surface molecules, which, together with the unique electrochemical properties of the BDNCD layer, provides the biosensors with a high detection sensitivity. Since Escherichia coli is an indicator of the fecal contamination of drinking water, it has also been chosen as a model organism for the development of this biosensor.
Education
- 2017 - now: UCT Prague, FTOP, Department of Water technology and environmental engineering, Ph.D. Student
- 2015 – 2017: UCT Prague, FTOP, Department of Water technology and environmental engineering, diploma thesis: „Inhibition effects of silver on microorganisms in wastewaters“
- 2012 – 2015: UCT Prague, FTOP, bachelor thesis: “Reduction of microbial populations by usage of nanoparticles“
Participation in teaching
- Hydrobiology and Microbiology Laboratory
Publications
Articles:
Čiháková, P., Zuzáková, J. a Říhová Ambrožová, J. 2021. Potenciálně negativní dopad dlouhodobého používání nanočástic stříbra ve vodním hospodářství. Chemické listy. 115, 11 (lis. 2021), 588-594.
Conference proceedings: